Saturday, September 10, 2011

Everything that you need to know about skin aging

Skin aging is a consequence of a combination of intrinsic and extrinsic skin aging determined by harmful exogenous factors.

Intrinsic skin aging

Intrinsic skin aging is also called chronological skin ageing and is caused by intrinsic factors such as age, gender, genetic predisposition and race. Intrinsic skin aging leads to decreasing physiological functionality of the skin such as decreased fibroblast activity due to collagen downregulation, low elsatin formation and low hyaluronic acid formation in the skin. It is also characterized by decrease in intra-dermal hydration and decreased skin elasticity and tonicity.




The following changes can be observed at various levels of skin due to intrinsic skin aging:


There is a decrease in cell density leading to reduced skin hydration and forming rough and dry skin in the epidermis.

The dermis also gets affected because there is a decrease in collagen fibers leading to thinning of dermis leading to fine lines and wrinkles. There is also a decrease in elastic fibers leading to decreased elasticity of the skin. A decrease in hyaluronic acid leads to less tonicity causing fine lines and wrinkles.

Extrinsic skin aging


Extrinsic skin aging is also called environmental aging. It typically occurs in skin areas exposed to environmental influences. It is superimposed on the symptoms of intrinsic aging and is characterized by coarse wrinkles and elastosis.

The common factors responsible for extrinsic skin aging are ultraviolet light, malnutrition, tobacco, alcohol abuse and inappropriate skincare measures.

Extrinsic factors leads to formation of reactive free radicals, also called reactive oxygen species which causes oxidation of many different cell elements such as DNA, proteins and membrane lipids. Expression of metalloproteinases is induced by UVA radiation which leads to collagen and elastin break down.

Crux of the matter


If you want to stop the watch and stay young, you need to take care of both intrinsic and extrinsic skin aging factors.

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